MOTS-c
Mitochondrial-derived peptide studied for insulin sensitivity, energy expenditure, and metabolic homeostasis.
Testing & quality
Every batch is supplier-tested for identity and purity and randomly verified by independent third-party HPLC and mass spectrometry.
About MOTS-c
MOTS-c is a very short peptide (16 building blocks) that the mitochondria — the tiny power plants inside cells — make on their own. Researchers study it because it flips on AMPK, the cell's main 'low fuel' switch that tells the body to burn sugar and fat for energy.
It is often called an 'exercise-mimic' peptide because cells treated with it show some of the same energy changes seen after exercise. Studies also look at how it behaves in stressed or aging cells. Supplied as a freeze-dried research powder at 99%+ purity for laboratory study only.
What animal studies have reported
These are outcomes published in peer-reviewed animal (preclinical) research on MOTS-c. They describe results seen in laboratory animals only.
- Protection against diet-induced weight gain in mice
- Improved insulin sensitivity and glucose handling
- Better exercise endurance in aged mice
Animal findings do not predict results in humans. Nothing here is a claim about human use — this product is sold for laboratory research only.
Compound classification
16-amino-acid mitochondrial-derived peptide (MDP) encoded in the 12S rRNA region of mtDNA.
Mechanism studied in the literature
Activates AMPK signaling and modulates folate-methionine cycle flux. Studied for its role as a metabolic regulator linking mitochondrial output to whole-cell energy state in preclinical models.
Research areas
- Mitochondrial bioenergetics
- AMPK / metabolic stress signaling
- Insulin sensitivity in cell and animal models
- Exercise and aging biology research
Storage
Lyophilized: -20°C, protected from light. Reconstituted: 2-8°C, use within 28 days.
Reconstitution (laboratory)
Reconstitute with bacteriostatic or sterile water for injection (USP grade).
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